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A new havanensin-type limonoid from Chisocheton macrophyllus
Applied Biological Chemistry ( IF 2.3 ) Pub Date : 2021-04-07 , DOI: 10.1186/s13765-021-00606-5
Nurlelasari , Intan Rahmayanti , Supriatno Salam , Agus Safari , Desi Harneti , Rani Maharani , Ace Tatang Hidayat , Mulyadi Tanjung , Rurini Retnowati , Yoshihito Shiono , Unang Supratman

A new havanensin-type limonoid, 16β-hydroxydysobinin (1), along with four known limonoids (2–5), have been isolated from the seeds of Chisocheton macrophyllus. The chemical structure of the new compound was determined by referencing spectroscopic data, and by comparison to those related spectra previously reported. Each compound was evaluated for their cytotoxic effects against Michigan Cancer Foundation-7 (MCF-7) breast cancer cells and display no significant activity.

中文翻译:

大叶Chisocheton的一种新的哈瓦那素型柠檬苦素

从Chisocheton macrophyllus的种子中分离出了一种新的哈芬菌素型柠檬苦素,即16β-羟基dysobinin(1),以及四种已知的柠檬苦素(2–5)。新化合物的化学结构是通过参考光谱数据并与先前报道的那些相关光谱进行比较来确定的。评估每种化合物对密歇根州癌症基金会7(MCF-7)乳腺癌细胞的细胞毒性作用,并且没有显着活性。
更新日期:2021-04-08
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