Risk factors for steroid-induced adverse psychological reactions and sleep problems in pediatric acute lymphoblastic leukemia: A systematic review,Psycho-Oncology

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Risk factors for steroid-induced adverse psychological reactions and sleep problems in pediatric acute lymphoblastic leukemia: A systematic review
Psycho-Oncology ( IF 3.3 ) Pub Date : 2021-04-06 , DOI: 10.1002/pon.5654
Annelienke M van Hulst ₁ , Shosha H M Peersmann ₁ , Erica L T van den Akker ₂ , Linda J Schoonmade ₃ , Marry M van den Heuvel-Eibrink ₁ , Martha A Grootenhuis ₁ , Raphaële R L van Litsenburg ₁

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Steroids play an essential role in treating pediatric acute lymphoblastic leukemia (ALL). The downside is that these drugs can cause severe side effects, such as adverse psychological reactions (APRs) and sleep problems, which can compromise health-related quality of life. This study aimed to systematically review literature to identify risk factors for steroid-induced APRs and sleep problems in children with ALL.

中文翻译：

类固醇引起的儿童急性淋巴细胞白血病不良心理反应和睡眠问题的危险因素：系统评价

类固醇在治疗小儿急性淋巴细胞白血病 (ALL) 中发挥着重要作用。不利的一面是，这些药物会引起严重的副作用，例如不良心理反应 (APR) 和睡眠问题，这会影响与健康相关的生活质量。本研究旨在系统地回顾文献，以确定 ALL 儿童类固醇诱导的 APR 和睡眠问题的危险因素。

更新日期：2021-04-06

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