The just-in time delivery of oxygen and nutrients to active brain regions to support function (functional hyperemia; FH) is mediated by not yet fully understood mechanisms collectively referred to as ‘neurovascular coupling’ (NVC). In a recent publication (eLife 2021) Thakore et al. provide profound mechanistic insight how the capillary endothelial transient receptor potential ankyrin 1 (TRPA1) channel contribute to blood flow control and functional hyperemia in the brain.

中文翻译：

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TRPA1 频道：“神经血管耦合”小镇的新手

将氧气和营养物及时输送到活跃的大脑区域以支持功能（功能性充血；FH）是由尚未完全理解的机制介导的，这些机制统称为“神经血管耦合”（NVC）。在最近的出版物（eLife 2021）中，Thakore 等人。提供深刻的机械见解毛细血管内皮瞬时受体电位锚蛋白 1 (TRPA1) 通道如何有助于大脑中的血流控制和功能性充血。