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Analytical capabilities of micellar liquid chromatography and application to residue and contaminant analysis: A review
Journal of Separation Science ( IF 2.8 ) Pub Date : 2021-04-03 , DOI: 10.1002/jssc.202001261
Ewelina Patyra 1 , Krzysztof Kwiatek 1
Affiliation  

Green chemistry is the use of chemistry to reduce or eliminate the use of generation of feedstocks, products, by-products, solvents, reagents, etc. that are hazardous to human health or the environment. One of the branches of green chemistry is micellar liquid chromatography. Micellar liquid chromatography is a reversed-phase liquid chromatographic mode with mobile phases containing a surfactant above its critical micellar concentration. The applications of micellar liquid chromatography for the determination of numerous compounds in pharmaceutical formulation, biological samples, food, environmental samples, and feeds have been growing rapidly. Micellar liquid chromatography technique has several advantages over other chromatographic techniques. Its main advantage is the small amount of organic modifiers used such as acetonitrile and methanol and the safety and recyclability of the mobile phase. In our work, we discuss the development of “green chemistry” and present what micellar liquid chromatography is. This article presents application methods with the use of micellar liquid chromatography for analysis on antibacterial substances, melamine, biogenic amines, plant protection products, flavonoids, as well as peptides in biological matrices such as milk, eggs, tissues, honey, and feed.

中文翻译:

胶束液相色谱的分析能力及其在残留物和污染物分析中的应用:综述

绿色化学是利用化学来减少或消除对人类健康或环境有害的原料、产品、副产品、溶剂、试剂等的使用。绿色化学的分支之一是胶束液相色谱。胶束液相色谱是一种反相液相色谱模式,流动相含有高于其临界胶束浓度的表面活性剂。胶束液相色谱用于测定药物制剂、生物样品、食品、环境样品和饲料中的多种化合物的应用正在迅速增长。胶束液相色谱技术与其他色谱技术相比有几个优点。其主要优点是乙腈、甲醇等有机改性剂用量少,流动相安全、可回收。在我们的工作中,我们讨论了“绿色化学”的发展,并介绍了什么是胶束液相色谱。本文介绍了使用胶束液相色谱法分析牛奶、鸡蛋、组织、蜂蜜和饲料等生物基质中的抗菌物质、三聚氰胺、生物胺、植物保护产品、黄酮类以及肽类的应用方法。
更新日期:2021-06-04
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