Per- and polyfluorinated alkyl substances are large class of man-made compounds known in the media as “forever chemicals”. In 2015, ASTM International published ASTM D7979, for the analysis of per- and polyfluorinated alkyl substances in non-potable water samples. This method extracts the substances by co-solvation with methanol and measures targeted compounds using liquid chromatography–tandem mass spectrometry. ASTM D7979 is a performance-based method that analyzes 31 compounds plus 14 isotopically labeled surrogates. The minimum reporting limit is approximately 10 ng/L with an analytical range of 10–200 ng/L for most compounds. Expected recovery of surrogates and spiked matrices is 70–130%. Samples containing high suspended solids can be analyzed with minimal interferences and potential loss of analyte. The method is consistent with ASTM and EPA's sustainable development goals by using reduced volumes of sample, solvent, and minimizing hazardous solvents and sample preparation materials while maintaining data quality and detection limits that are suitable for the intended use. This paper covers the rationale, outlines some of the challenges associated with analysis of per- and polyfluorinated alkyl substances, and describes the steps taken by the ASTM Committee D19 task group to develop, optimize, and validate this method.

中文翻译：

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ASTM D7979 审查通过与甲醇共溶剂化并使用液相色谱-串联质谱法分析非饮用水中的全氟和多氟烷基物质

全氟和多氟烷基物质是一大类人造化合物，在媒体中被称为“永远的化学品”。2015 年，ASTM International 发布了 ASTM D7979，用于分析非饮用水样品中的全氟和多氟烷基物质。该方法通过与甲醇共溶剂化提取物质，并使用液相色谱-串联质谱法测量目标化合物。ASTM D7979 是一种基于性能的方法，可分析 31 种化合物和 14 种同位素标记的替代物。大多数化合物的最低报告限约为 10 ng/L，分析范围为 10–200 ng/L。替代品和加标基质的预期回收率为 70-130%。可以分析含有高悬浮固体的样品，同时将干扰和分析物的潜在损失降至最低。该方法与 ASTM 和 EPA 的可持续发展目标一致，使用更少的样品、溶剂，并最大限度地减少有害溶剂和样品制备材料，同时保持适合预期用途的数据质量和检测限。本文介绍了基本原理，概述了与全氟和多氟烷基物质分析相关的一些挑战，并描述了 ASTM 委员会 D19 任务组为开发、优化和验证该方法所采取的步骤。