Abstract

Seven new monoterpene alkaloids (1−7), along with 18 known analogues, were isolated from an aqueous decoction of the hook-bearing stems of Uncaria rhynchophylla (Gou-teng). Their structures were determined by spectroscopic data analysis and electronic circular dichroism (ECD) calculations. Compound 1 is the first monoterpene 22-norindoloquinolizidine alkaloid with a ketene unit, while 2 and 3 are unusual indoloquinolizidine alkaloids having an oxazinane ring.

中文翻译：

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钩藤Uncaria rhynchophylla带钩茎的水提物中的次生物碱

摘要

七个新单萜生物碱（1 - 7）中，用18个已知类似物一起，被从钩轴承的水煎剂分离茎的钩藤（苟腾）。它们的结构通过光谱数据分析和电子圆二色性（ECD）计算确定。化合物1是具有烯酮单元的第一个单萜22-去甲吲哚并喹唑烷生物碱，而化合物2和3是具有恶嗪烷环的不寻常的吲哚并喹喔啉生物碱。