There is growing worry that drinking water can be affected by contaminants of emerging concern (CECs), potentially threatening human health. In this study, a wide range of CECs (n = 177), including pharmaceuticals, pesticides, perfluoroalkyl substances (PFASs) and other compounds, were analysed in raw water and in drinking water collected from drinking water treatment plants (DWTPs) in Europe and Asia (n = 13). The impact of human activities was reflected in large numbers of compounds detected (n = 115) and high variation in concentrations in the raw water (range 15-7995 ng L⁻¹ for ∑₁₇₇CECs). The variation was less pronounced in drinking water, with total concentration ranging from 35 to 919 ng L⁻¹. Treatment efficiency was on average 65 ± 28%, with wide variation between different DWTPs. The DWTP with the highest ∑CEC concentrations in raw water had the most efficient treatment procedure (average treatment efficiency 89%), whereas the DWTP with the lowest ∑₁₇₇CEC concentration in the raw water had the lowest average treatment efficiency (2.3%). Suspect screening was performed for 500 compounds ranked high as chemicals of concern for drinking water, using a prioritisation tool (SusTool). Overall, 208 features of interest were discovered and three were confirmed with reference standards. There was co-variation between removal efficiency in DWTPs for the target compounds and the suspected features detected using suspect screening, implying that removal of known contaminants can be used to predict overall removal of potential CECs for drinking water production. Our results can be of high value for DWTPs around the globe in their planning for future treatment strategies to meet the increasing concern about human exposure to unknown CECs present in their drinking water.

人们越来越担心饮用水可能会受到新出现的污染物（CEC）的影响，从而可能威胁到人类健康。在这项研究中，对欧洲和欧洲的原水和饮用水处理厂（DWTP）收集的饮用水中的多种CEC（n = 177）进行了分析，包括药品，农药，全氟烷基物质（PFAS）和其他化合物。亚洲（n = 13）。人类活动的影响反映在检测到的大量化合物（n = 115）和原水中浓度的高变化（对于∑ ₁₇₇ CEC，范围为15-7995 ng L ^-1）。饮用水中的变化不明显，总浓度范围为35至919 ng L^-1。治疗效率平均为65±28％，不同的DWTP之间差异很大。原水中∑CEC浓度最高的DWTP的处理程序最有效（平均处理效率为89％），而∑ ₁₇₇最低的DWTP原水中的CEC浓度具有最低的平均处理效率（2.3％）。使用优先级排序工具（SusTool）对可疑饮用水中排名最高的500种化合物进行了可疑筛查。总体上，发现了208个感兴趣的特征，并用参考标准确认了三个。在目标化合物的DWTP中去除效率与使用可疑筛查检测到的可疑特征之间存在协变量，这意味着已知污染物的去除可用于预测饮用水生产中潜在CEC的总体去除。我们的结果对于全球DWTP在规划未来的治疗策略方面具有很高的价值，以满足人们日益关注其饮用水中存在的未知CEC的担忧。