Maternal immune activation alters adult behavior, intestinal integrity, gut microbiota and the gut inflammation,Brain and Behavior

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Maternal immune activation alters adult behavior, intestinal integrity, gut microbiota and the gut inflammation
Brain and Behavior ( IF 3.1 ) Pub Date : 2021-04-01 , DOI: 10.1002/brb3.2133
Wenqiang Li _{1,

2,

3} , Mengxue Chen _{1,

2,

3} , Xia Feng _{1,

2,

3} , Meng Song _{1,

2,

3} , Minglong Shao _{1,

2,

3} , Yongfeng Yang _{1,

2,

3} , Luwen Zhang _{1,

2,

3} , Qing Liu _{1,

2,

3} , Luxian Lv _{1,

2,

3,

4} , Xi Su _{1,

2,

3}

Affiliation

Schizophrenia is characterized by several core behavioral features, in which the gastrointestinal symptoms are frequently reported. Maternal immune activation (MIA) has been developed in a rodent model to study neurodevelopmental disorders such as schizophrenia. However, the changes in the gut environment of MIA rats remain largely unknown.

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