Abstract

The objective of this study is to synthesize QD-embedded molecularly imprinted membranes (MIMs) with 2-mercaptoethanol-capped manganese-doped zinc sulfide quantum dots (ME-capped Mn-doped ZnS QDs) through chemical precipitation followed by surface molecular imprinting. For the synthesis of the MIMs, the weight of ME-capped Mn-doped ZnS QDs was first manipulated, followed by their characterization through transmission electron microscopy (TEM), zeta potential, hydrodynamic particle size, particle size distribution, and Fourier-transform infrared spectroscopy (FTIR). The resultant MIM was characterized by fluorescence intensity and showed an emission peak of 600 nm with an excitation wavelength of 300 nm. Besides, increments in QDs were found to elevate the fluorescence intensity of the MIM, contributing to an improved fluorescence quantum yield. This article indicates that molecularly-imprinted QD-based sensors offer promising biomedical potential in diagnoses and treatment.

摘要

本研究的目的是通过化学沉淀和表面分子印迹合成 2-巯基乙醇封端的锰掺杂硫化锌量子点（ME 封端的锰掺杂 ZnS 量子点）嵌入量子点的分子印迹膜（MIM）。对于 MIM 的合成，首先操纵 ME 封端的 Mn 掺杂 ZnS 量子点的重量，然后通过透射电子显微镜 (TEM)、zeta 电位、流体动力学粒度、粒度分布和傅里叶变换红外对其进行表征光谱学（FTIR）。所得 MIM 以荧光强度为特征，发射峰为 600 nm，激发波长为 300 nm。此外，发现量子点的增加会提高 MIM 的荧光强度，从而有助于提高荧光量子产率。