Internuclear ophthalmoplegia is a dysfunction of conjugate eye movements, caused by lesions affecting the medial longitudinal fasciculus (MLF). Multiple sclerosis (MS) and ischemic stroke represent the most common pathophysiologies. While magnetic resonance imaging (MRI) allows for localizing lesions affecting the MLF, comprehensive comparative studies exploring potential different spatial characteristics of lesions affecting the MLF are missing until now.

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多发性硬化症或缺血性中风患者核内眼肌麻痹相关病变的MRI地形图

核内眼肌麻痹是由影响内侧纵筋膜（MLF）的病变引起的共轭眼球运动功能障碍。多发性硬化症（MS）和缺血性中风代表最常见的病理生理。虽然磁共振成像（MRI）可以对影响MLF的病变进行定位，但是到目前为止，缺乏探索影响MLF的潜在不同空间特征的综合比较研究。