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Simultaneous Determination of Eight Chemical Components in Angelicae Sinensis Radix and Its Herbal Products by QAMS
Journal of Analytical Methods in Chemistry ( IF 2.3 ) Pub Date : 2021-03-31 , DOI: 10.1155/2021/7178982
Yu Zhang 1, 2 , Qian Li 1 , Yanmei Feng 1 , Lan Yang 1 , Qi Wang 1 , Yehong Guo 1 , Daiyu Qiu 1
Affiliation  

A HPLC method has been developed for simultaneously detecting chlorogenic acid, ferulic acid, senkyunolide I, senkyunolide H, coniferyl ferulate, senkyunolide A, ligustilide, and levistolide A in Angelicae Sinensis Radix through quantitative analysis of multicomponents by single-marker (QAMS) method with ferulic acid as internal standard substance. The relative analysis correction factors of each component in Angelicae Sinensis Radix have good reproducibility under different chromatography conditions. In addition, no significant difference of results was found between quantitative analysis of multicomponents by single-marker (QAMS) method and external standard method in determining content of these components of different Angelicae Sinensis Radix and its 12 kinds of preparations. As a result, the established QAMS method for Angelicae Sinensis Radix analysis with ferulic acid as internal standard substance is accurate and feasible, which could be used as an effective and economical method to control quality of Angelicae Sinensis Radix and its herbal products.

中文翻译:

QAMS同时测定当归及其中草药中的八种化学成分

建立了一种同时测定当归中多组分的含量的高效液相色谱方法,该方法同时通过多标记物的定量分析同时检测当归中的绿原酸,阿魏酸,山茱yun内酯I,山茱ol内酯H,针叶树阿魏酸酯,山茱ol内酯A,li本内酯和左旋多杀菌素A。阿魏酸为内标物质。当归中各成分的相对分析校正因子在不同色谱条件下均具有良好的重现性。此外,在测定当归和12种制剂中这些成分的含量时,单标记(QAMS)法和外标法对多成分进行定量分析没有发现显着差异。因此,
更新日期:2021-03-31
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