Background

There is increasing interest in the association between perinatal depression and diet including whether diet may have an impact on depressive symptoms and equally whether depression influences diet. Furthermore, whether pharmacological treatment of depression with antidepressant medication also may influence diet.

Methods

We examine diet, perinatal depression, and antidepressant use in 442 women recruited in early pregnancy and followed until 12 months postpartum as part of the Mercy Pregnancy Emotional Wellbeing Study. Measures included Structured Clinical Interview for the DSM at recruitment in early pregnancy and comprehensive dietary intake questions, Edinburgh Postnatal Depression Scale, and self-report and recorded antidepressant use at third trimester and 6 and 12 months postpartum.

Results

This study found that those women with untreated, current depression in pregnancy had higher unhealthy takeaway food intake across the perinatal period compared to those taking antidepressant medication or healthy control women, albeit the overall effects were small and the clinical significance unknown. Higher depressive symptoms in the postpartum were also associated with higher takeaway intake. There was no difference in fruit and vegetable intake between the three groups and intake was highest for all women late in pregnancy and declined in the postpartum period. In all, women's takeaway food intake increased from pregnancy across the postpartum.

Limitations

Lack of information on pre-pregnancy diet.

Conclusions

Unhealthy takeaway intake was found to be associated with depression; however, for those women who took antidepressant treatment, their diet patterns were similar to healthy controls. Future research should examine the relationship of treatments for depression in addition to depression and associated dietary behaviours.

中文翻译：

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在MPEWS怀孕队列研究中，孕妇以及产后以及整个产后前12个月的孕妇饮食，抑郁和抗抑郁药治疗

背景

围产期抑郁症与饮食之间的联系越来越引起人们的关注，包括饮食是否可能对抑郁症状产生影响以及抑郁是否会影响饮食。此外，用抗抑郁药进行抑郁症的药理学治疗是否也会影响饮食。

方法

我们研究了442名在早期妊娠中招募的妇女的饮食，围产期抑郁症和抗抑郁药的使用情况，并将其随访至产后12个月，作为Mercy怀孕情绪健康研究的一部分。措施包括在妊娠早期和综合饮食摄入量问题上进行DSM的结构化临床访谈，爱丁堡产后抑郁量表以及自我报告和记录的妊娠晚期，产后6和12个月的抗抑郁药使用情况。

结果

这项研究发现，与那些服用抗抑郁药或健康对照组的妇女相比，那些目前未接受治疗且当前处于妊娠抑郁状态的妇女在围产期的不健康外卖食物摄入量更高，尽管总体效果很小并且临床意义尚不清楚。产后抑郁症状较高也与较高的外卖摄入量有关。两组之间的水果和蔬菜摄入量没有差异，并且所有摄入量在怀孕后期的妇女中最高，而在产后下降。总体而言，妇女在整个产后从怀孕开始的外卖食物摄入量就增加了。

局限性

孕前饮食缺乏信息。

结论

发现不健康的外卖摄入量与抑郁症有关。但是，对于接受抗抑郁药治疗的女性，其饮食模式与健康对照者相似。未来的研究应该研究抑郁症与抑郁症及相关饮食行为之间的关系。