A significant proportion of people with schizophrenia are characterized by impaired ability to socially engage with others. The development of effective interventions for social functioning remains a central therapeutic challenge. Cognitive-behavioral social skills training (CBSST) has been found to improve social functioning in schizophrenia, but with only medium effect sizes. Intranasal oxytocin also has prosocial effects, but also only with modest effect sizes. This study assessed whether the addition of intranasal oxytocin to CBSST can strengthen their impact on social function.

中文翻译：

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结合催产素和认知行为社交技能训练对精神分裂症患者的社会功能。

很大一部分精神分裂症患者的特点是与他人交往的能力受损。开发有效的社会功能干预措施仍然是一个核心的治疗挑战。已发现认知行为社交技能训练 (CBSST) 可改善精神分裂症患者的社交功能，但效果中等。鼻内催产素也具有亲社会作用，但也仅具有适度的作用大小。本研究评估了在 CBSST 中添加鼻内催产素是否可以增强其对社会功能的影响。