Serial chest computed tomography (CT) scans are used to detect coronavirus disease 2019 (COVID-19) pneumonia and monitor the disease course. This study investigates relationship between total severity score by first chest CT and the outcome of coronavirus COVID-19 patients with coronary artery disease (CAD). A total of 48 patients with a history of CAD (mean age=60.83±3.06 years, 75% male) with positive real-time reverse transcription-polymerase chain reaction for COVID-19 were included. Outcome was defined as acute respiratory distress syndrome or death. The unadjusted and adjusted effects of the CT score on the outcome were reported through odds ratio (OR) with 95% confidence interval (CI). Outcome occurred in 17 (35.5%) patients (8 deaths). The CT score was directly and significantly correlated with the outcome in the univariate analysis (OR 1.38, 95% CI 1.12–1.70; P=0.003) and remained significant after adjustment for diabetes, hypertension, body mass index, and serum level of highly sensitive C-reactive protein (OR 1.51, 95% CI 1.11–2.05; P=0.009). Outcome rate was 24.1% in patients with a CT score <2.5, whereas it was 8.3% in patients with a CT score>2.5. The first chest CT score could be a robust predictor of adverse events in confirmed COVID-19 patients with coronary artery disease.

中文翻译：

---

预测已确诊的COVID-19冠心病患者的预后：首次胸部X线断层扫描的关键作用

连续胸部计算机断层扫描（CT）扫描用于检测冠状病毒病2019（COVID-19）肺炎并监测病程。这项研究调查了首次胸部CT的总严重程度评分与冠状病毒COVID-19冠心病（CAD）患者的预后之间的关系。总共纳入了48例具有CAD历史（平均年龄= 60.83±3.06岁，男性75％）且COVID-19实时反转录聚合酶链反应阳性的患者。结果定义为急性呼吸窘迫综合征或死亡。通过比值比（OR）和95％置信区间（CI）报告了CT评分对结局的未经调整和调整的影响。结果发生于17（35.5％）位患者（8例死亡）。CT评分与单因素分析的结果直接且显着相关（OR 1。38，95％CI 1.12–1.70; P = 0.003），并在调整糖尿病，高血压，体重指数和血清中高敏C反应蛋白水平后仍然显着（OR 1.51，95％CI 1.11–2.05； P = 0.009）。CT评分<2.5的患者的结果率为24.1％，而CT评分> 2.5的患者的结果率为8.3％。首次胸部CT评分可能是确诊的COVID-19冠心病患者不良事件的有力预测指标。