ABSTRACT

Experimental water-to-methyl ethyl ketone partition coefficients have been determined for 34 different organic solutes at ambient room temperature based on gas–liquid chromatographic measurements. Updated Abraham model correlations were determined for describing solute transfer into methyl ethyl ketone by combining the measured partition coefficient data determined in the present study with published experimental values taken from chemical and engineering literature. Experimental data for 48 compounds were used in determining the revised Abraham model correlations. The revised mathematical correlations were determined to back-calculate the observed partition coefficient data to within an overall average standard deviation of 0.17 log units or less. The partitioning characteristics of the water-to-methyl ethyl ketone system are compared to the characteristics of two other biphasic water-to-ketone partitioning systems.

摘要

基于气液色谱测量，已在环境室温下确定了 34 种不同有机溶质的实验性水与甲基乙基酮分配系数。通过将本研究中确定的测量分配系数数据与从化学和工程文献中获取的已发表实验值相结合，确定了更新的亚伯拉罕模型相关性，以描述溶质转移到甲乙酮中。48 种化合物的实验数据用于确定修正后的亚伯拉罕模型相关性。确定修改后的数学相关性以将观察到的分配系数数据反算到 0.17 对数单位或更小的总体平均标准偏差内。