This mini review provides a detailed outline of studies that have used multimodal approaches in non-invasive brain stimulation to investigate the pathophysiology of the three common movement disorders namely, essential tremor, Parkinson’s disease and dystonia. Since it is now known that movement disorders are associated with altered functional connectivity in the cortical and subcortical brain networks, integrating different non-invasive brain stimulation and recording methods would be highly valuable in enhancing our understanding of their pathophysiology. Technological advancements in the field have enabled novel combinations of non-invasive brain stimulation and neuroimaging/neurophysiological methods which could have immense potential in the development of diagnostic tools and treatment strategies for movement disorders.

中文翻译：

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挖掘多模式非侵入性脑刺激的潜力，以阐明运动障碍的病理生理学

这份简短的综述详细介绍了在无创性脑刺激中使用多模式方法研究三种常见运动障碍（原发性震颤，帕金森氏病和肌张力障碍）的病理生理的研究概况。由于现在已知运动障碍与皮质和皮质下脑网络中功能连接性的改变有关，因此整合不同的非侵入性脑刺激和记录方法在增进我们对其病理生理学的理解方面将具有非常重要的价值。该领域的技术进步已经实现了非侵入性脑刺激和神经影像/神经生理学方法的新颖组合，这些组合在开发运动障碍的诊断工具和治疗策略方面可能具有巨大的潜力。