Objectives Physical inactivity is a risk factor for premature mortality and several non-communicable diseases. The purpose of this study was to estimate the global burden associated with physical inactivity, and to examine differences by country income and region. Methods Population-level, prevalence-based population attributable risks (PAR) were calculated for 168 countries to estimate how much disease could be averted if physical inactivity were eliminated. We calculated PARs (percentage of cases attributable to inactivity) for all-cause mortality, cardiovascular disease mortality and non-communicable diseases including coronary heart disease, stroke, hypertension, type 2 diabetes, dementia, depression and cancers of the bladder, breast, colon, endometrium, oesophagus, stomach and kidney. Results Globally, 7.2% and 7.6% of all-cause and cardiovascular disease deaths, respectively, are attributable to physical inactivity. The proportions of non-communicable diseases attributable to physical inactivity range from 1.6% for hypertension to 8.1% for dementia. There was an increasing gradient across income groups; PARs were more than double in high-income compared with low-income countries. However, 69% of total deaths and 74% of cardiovascular disease deaths associated with physical inactivity are occurring in middle-income countries, given their population size. Regional differences were also observed, with the PARs occurring in Latin America/Caribbean and high-income Western and Asia-Pacific countries, and the lowest burden occurring in Oceania and East/Southeast Asia. Conclusion The global burden associated with physical inactivity is substantial. The relative burden is greatest in high-income countries; however, the greatest number of people (absolute burden) affected by physical inactivity are living in middle-income countries given the size of their populations. No data are available. The study specific summary data included in this study can be obtained from the corresponding author, peter.katzmarzyk@pbrc.edu

中文翻译：

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低收入、中等收入和高收入国家缺乏身体活动和非传染性疾病负担

目标 缺乏身体活动是过早死亡和几种非传染性疾病的风险因素。本研究的目的是估计与缺乏身体活动相关的全球负担，并检查不同国家收入和地区的差异。方法 计算了 168 个国家的人口水平、基于患病率的人口归因风险 (PAR)，以估计如果消除身体不活动可以避免多少疾病。我们计算了全因死亡率、心血管疾病死亡率和非传染性疾病（包括冠心病、中风、高血压、2 型糖尿病、痴呆、抑郁症和膀胱癌、乳腺癌、结肠癌）的 PAR（归因于不活动的病例百分比） 、子宫内膜、食道、胃和肾。结果在全球范围内，分别为 7.2% 和 7。分别有 6% 的全因死亡和心血管疾病死亡可归因于缺乏身体活动。因缺乏身体活动而导致的非传染性疾病的比例从高血压的 1.6% 到痴呆症的 8.1% 不等。收入群体之间的梯度越来越大；与低收入国家相比，高收入国家的 PAR 高出一倍以上。然而，考虑到人口规模，69% 的总死亡人数和 74% 的与缺乏身体活动相关的心血管疾病死亡发生在中等收入国家。还观察到区域差异，PARs 发生在拉丁美洲/加勒比以及高收入的西方和亚太国家，而最低负担发生在大洋洲和东亚/东南亚。结论 与缺乏身体活动相关的全球负担是巨大的。高收入国家的相对负担最大；然而，考虑到人口规模，受缺乏身体活动影响的人数最多（绝对负担）生活在中等收入国家。没有可用的数据。本研究包含的研究具体总结数据可从通讯作者peter.katzmarzyk@pbrc.edu获得