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Melancholic Features in Bipolar Depression and Response to Lamotrigine: A Pooled Analysis of Five Randomized Placebo-Controlled Trials.
Journal of Clinical Psychopharmacology ( IF 2.9 ) Pub Date : 2021-03-18 , DOI: 10.1097/jcp.0000000000001393 Evyn M Peters 1 , Yanbo Zhang 2 , Rohit Lodhi 1 , Hua Li 3 , Lloyd Balbuena 1
Journal of Clinical Psychopharmacology ( IF 2.9 ) Pub Date : 2021-03-18 , DOI: 10.1097/jcp.0000000000001393 Evyn M Peters 1 , Yanbo Zhang 2 , Rohit Lodhi 1 , Hua Li 3 , Lloyd Balbuena 1
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A pilot study suggested lamotrigine may be more effective for bipolar depression with melancholic features. We tested this hypothesis in a pooled analysis of 5 randomized double-blind placebo-controlled trials of lamotrigine for acute bipolar depression.
中文翻译:
双相抑郁症的忧郁特征和对拉莫三嗪的反应:五项随机安慰剂对照试验的汇总分析。
一项初步研究表明,拉莫三嗪可能对具有忧郁特征的双相抑郁症更有效。我们在对 5 项拉莫三嗪治疗急性双相抑郁症的随机双盲安慰剂对照试验的汇总分析中检验了这一假设。
更新日期:2021-03-31
中文翻译:
双相抑郁症的忧郁特征和对拉莫三嗪的反应:五项随机安慰剂对照试验的汇总分析。
一项初步研究表明,拉莫三嗪可能对具有忧郁特征的双相抑郁症更有效。我们在对 5 项拉莫三嗪治疗急性双相抑郁症的随机双盲安慰剂对照试验的汇总分析中检验了这一假设。