Arterial spin labeling (ASL) is an MRI technique measuring brain perfusion using magnetically labeled blood as a tracer. The clinical utility of ASL for presurgical evaluation in non-lesional epilepsy as compared with the quantitative analysis of interictal [¹⁸F] fluorodeoxyglucose PET (FDG-PET) was studied. In 10 patients (4 female; median age 29 years) who underwent a complete presurgical evaluation followed by surgical resection, the presurgical FDG-PET and ASL scans were compared with the resection masks using asymmetry index (AI) maps. The positive predictive value (PPV) and sensitivity (SEN), were calculated from the number of voxels inside the mask (true positive), and outside the mask (false positive). The comparison of the PPVs showed better PPV in 6 patients using ASL and in 2 patients with PET. SEN was better in 4 patients using ASL and in 5 patients with PET. According to the Wilcoxon signed rank test for PPV (p = 0.74) and for SEN (p = 0.43), these methods have similar predictive power. ASL is a useful method for presurgical evaluation in non-lesional epilepsy. The main benefits of ASL over PET are that it avoids radiation exposure for patients, and it offers lower costs, higher availability, and better time efficiency.

动脉自旋标记（ASL）是一种MRI技术，使用磁性标记的血液作为示踪剂来测量大脑灌注。ASL与非病灶性癫痫的定量分析相比，在非病灶性癫痫术前评估中的临床应用[ ¹⁸研究了F]氟脱氧葡萄糖PET（FDG-PET）。在接受完整的术前评估并进行手术切除的10例患者（4名女性；中位年龄为29岁）中，使用不对称指数（AI）图将术前FDG-PET和ASL扫描与切除面罩进行了比较。从面罩内部（真阳性）和面罩外部（假阳性）的体素数计算出阳性预测值（PPV）和灵敏度（SEN）。PPV的比较显示，在6例使用ASL的患者和2例PET的患者中，PPV更好。SEN在4例使用ASL的患者和5例PET的患者中更好。根据PPV（p = 0.74）和SEN（p = 0.43）的Wilcoxon符号秩检验，这些方法具有相似的预测能力。ASL是非病灶性癫痫的术前评估的有用方法。