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Magnetic resonance imaging parameters in predicting the ablative efficiency of high-intensity focused ultrasound for uterine fibroids
International Journal of Hyperthermia ( IF 3.0 ) Pub Date : 2021-03-30 , DOI: 10.1080/02656736.2021.1904152
Chunmei Gong 1, 2 , Zhenjiang Lin 1, 2 , Fajin Lv 3 , Lian Zhang 1, 2 , Zhibiao Wang 1, 2
Affiliation  

Abstract

Objective

To evaluate the role of quantitative MRI parameters in predicting HIFU ablation results for uterine fibroids.

Material and methods

A total of 245 patients with uterine fibroids who underwent HIFU treatment in Chongqing Haifu Hospital were reviewed retrospectively. The patients were divided into two groups according to the non-perfused volume (NPV) ratio which was either higher or lower than 80%. The MRI parameters were measured, and a logistical regression analysis was performed to investigate the potential predictors associated with the NPV ratio. Receiver operating characteristics (ROC) analysis was used to determine the cut off value for MRI parameters in predicting a high NPV ratio.

Results

The subcutaneous fat thickness in the group of patients with an NPV ratio over 80% was significantly thinner than that in the group of patients with an NPV ratio less than 80% (15 mm versus 21 mm). The signal intensity ratio of fibroids to skeletal muscle on T2WI was significantly lower in the group of patients with an NPV ratio over 80% compared with the group with an NPV ratio lower than 80% (2.46 versus 3.23). The signal intensity ratio of fibroid to skeletal muscle correlated negatively with the NPV ratio and positively with the energy efficiency factor (EEF). The cut off value of signal intensity ratio of fibroid to muscle for predicting the NPV ratio over 80% is 3.045.

Conclusion

The signal intensity ratio of fibroid to skeletal muscle on T2WI can be used as a factor for predicting the effectiveness of HIFU ablation of uterine fibroids.



中文翻译:

磁共振成像参数预测高强度聚焦超声对子宫肌瘤的消融效率

摘要

客观的

评估定量MRI参数在预测子宫肌瘤HIFU消融结果中的作用。

材料与方法

回顾性分析重庆海福医院行HIFU治疗的245例子宫肌瘤患者。根据高于或低于80%的非灌注量(NPV)比例将患者分为两组。测量MRI参数,并进行逻辑回归分析以研究与NPV比相关的潜在预测因子。接收器工作特征(ROC)分析用于确定MRI参数的临界值,以预测高NPV比。

结果

NPV比率大于80%的患者组的皮下脂肪厚度明显小于NPV比率小于80%的患者的皮下脂肪厚度(15毫米对21毫米)。NPV比率超过80%的患者组中T2WI上肌瘤与骨骼肌的信号强度比显着低于NPV比率低于80%的患者(2.46对3.23)。肌瘤与骨骼肌的信号强度比率与NPV比率呈负相关,与能量效率因子(EEF)呈正相关。用于预测NPV比率超过80%的肌瘤与肌肉的信号强度比率的截止值为3.045。

结论

T2WI上肌瘤与骨骼肌的信号强度比可用作预测子宫肌瘤HIFU消融效果的因素。

更新日期:2021-03-30
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