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Metal-free synthesis of indolo[2,3- b ]indoles through aerobic cascade dehydrogenative aromatization/oxidative annulation
Green Synthesis and Catalysis ( IF 8.2 ) Pub Date : 2021-3-1 , DOI: 10.1016/j.gresc.2021.01.004
Pingyu Jiang , Shanping Chen , Huawen Huang , Kai Hu , Yi Xia , Guo-Jun Deng

A convenient method for the rapid construction of indolo[2,3-b]indoles has been developed. This cascade reaction involving condensation, dehydroaromatization, and oxidative annulation was achieved in a one-pot TMSI/DMSO system, providing a diversity of functionalized indolo[2,3-b]indoles in satisfactory yields under facile metal-free conditions. The present protocol provides a straightforward approach to access structurally valuable indolo[2,3-b], indoles.

中文翻译:

好氧级联脱氢芳构化/氧化环合法无金属合成吲哚[2,3-b]吲哚

已经开发了一种快速构建吲哚[2,3-b]吲哚的简便方法。该反应涉及缩合,脱氢芳构化和氧化环化反应,是通过一锅TMSI / DMSO系统完成的,在无金属条件下以令人满意的收率提供了多种官能化的吲哚[2,3-b]吲哚。本协议提供了一种直接的方法来访问结构上有价值的吲哚[2,3-b]吲哚。
更新日期:2021-03-30
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