A manganese/NaOPh co-catalyzed C2-selective C–H conjugate addition of indoles to α,β-unsaturated carbonyls has been developed. The reaction features very high atom economy in which no stoichiometric reagents/additives were employed. The crucial role of sodium phenolate (NaOPh) as a synergetic catalyst was revealed in the reaction screening process and mechanistic experiments.

中文翻译：

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锰/ NaOPh共同催化吲哚向不饱和羰基的C2选择性C–H共轭加成反应

已经开发了锰/ NaOPh将吲哚的C2选择性C–H共轭共轭加成到α，β-不饱和羰基上。该反应具有非常高的原子经济性，其中不使用化学计量的试剂/添加剂。在反应筛选过程和机理实验中揭示了酚钠（NaOPh）作为协同催化剂的关键作用。