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A Simple and High‐Accuracy PID‐Based Temperature Control System for Magnetic Hyperthermia Using Fiber Optic Thermometer
IEEJ Transactions on Electrical and Electronic Engineering ( IF 1.0 ) Pub Date : 2021-03-29 , DOI: 10.1002/tee.23361
Akihiro Shikano 1 , Loi Tonthat 1 , Shin Yabukami 1
Affiliation  

Magnetic hyperthermia is very promising cancer therapy in which heating temperature is expected to be a key determinant for its success. Herein, we present a simple, real‐time, and high‐accuracy proportional‐integral‐derivative‐based temperature control system for magnetic hyperthermia using widely‐used induction heater and fiber optic thermometer. Our in vitro result shows that the temperature of clinically‐approved Resovist® (0.5 ml) was accurately controlled with very small overshoot (e.g., 45.0 ± 0.07 °C and 55.0 ± 0.11°C for low‐ and high‐temperature magnetic hyperthermia). Our system has the potential to be used for magnetic hyperthermia either alone or together with other cancer treatment modalities for basic and clinical studies. © 2021 Institute of Electrical Engineers of Japan. Published by Wiley Periodicals LLC.

中文翻译:

基于光纤温度计的简单,高精度,基于PID的磁疗温度控制系统

磁热疗法是非常有前途的癌症疗法,其中加热温度有望成为其成功的关键因素。在此,我们介绍了一种使用广泛使用的感应加热器和光纤温度计的,用于磁热疗的简单,实时且高精度的比例积分微分温度控制系统。我们的体外结果表明,经过临床批准的Res​​ovist®(0.5 ml)的温度可通过非常小的过冲(例如,对于低温和高温磁热疗法为45.0±0.07°C和55.0±0.11°C)进行精确控制。我们的系统具有单独或与其他癌症治疗方式一起用于基础和临床研究的磁热疗潜力。©2021日本电气工程师学会。由Wiley Periodicals LLC发布。
更新日期:2021-04-22
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