Electroporation has become a powerful technological platform for the electromanipulation of cells and tissues for various medical and biotechnological applications. Recently, nanoporation based on nanosecond pulsed electric fields (nsPEFs) has gained great attention due to its potential to permeabilize the membrane of small vesicles. Here, the authors propose and characterize, both experimentally and through multiphysics modeling, a grounded coplanar waveguide compliant with the wideband requirements for nanosecond pulses to be used for experiments of drug delivery with liposomes activated by nsPEFs.

中文翻译：

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用于脂质体的纳米电穿孔接地共面波导的实验和数值表征

电穿孔已成为一个强大的技术平台，用于对各种医学和生物技术应用中的细胞和组织进行电操作。最近，基于纳秒脉冲电场 (nsPEFs) 的纳米穿孔因其具有透化小囊泡膜的潜力而备受关注。在这里，作者通过实验和多物理场建模提出并描述了一种接地共面波导，该波导符合纳秒脉冲的宽带要求，用于通过 nsPEF 激活的脂质体进行药物递送实验。