Several observational studies have shown that hyperuricemia is associated with chronic kidney disease (CKD) progression and is a potential therapeutic target in people with CKD. This review discusses the results of three recently published placebo-controlled randomized trials evaluating the effect of urate-lowering treatment on the progression of CKD with at least 2 years of follow-up.

中文翻译：

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关于降尿酸治疗对肾脏疾病进展影响的最新证据。

几项观察性研究表明，高尿酸血症与慢性肾病 (CKD) 进展有关，是 CKD 患者的潜在治疗靶点。本综述讨论了最近发表的三项安慰剂对照随机试验的结果，这些试验评估了降尿酸治疗对 CKD 进展的影响，随访至少 2 年。