This systematic appraisal explores the literature surrounding treatment adherence in teenagers and young adults (TYAs) with cancer, with the aim of identifying influential factors that could affect adherence rates. This area is particularly important due to the increased risk of relapse and death associated with nonadherent behavior. In addition, TYAs are found to be the age group least likely to adhere to medical regimes. A comprehensive review of the literature was conducted and seven studies met the inclusion criteria, the articles were then critiqued using a data extraction form and eight themes were generated and discussed. This review highlights the complexities and difficulties in measuring adherence, as well as the key factors affecting adherence, before identifying implications for practice. Good communication and relationships are crucial between all parties involved in TYAs’ care including the patients, professionals, parents, and peers. A model of adherence was adapted on the basis of the result of the systematic review, other literature pertaining to adherence in TYAs, and the clinical experience of the authors. Personal factors and external factors, along with treatment factors and interactions with the system all have an effect on the patient's response or ability to adhere. It is apparent that there is a need for more high-quality qualitative and quantitative research in this area, with an emphasis on finding interventions that directly improve adherence specific to this age group.

该系统评估探讨了有关青少年和年轻成人 (TYA) 癌症治疗依从性的文献，目的是确定可能影响依从率的影响因素。由于与不依从行为相关的复发和死亡风险增加，该区域尤为重要。此外，发现 TYA 是最不可能遵守医疗制度的年龄组。对文献进行了全面审查，七项研究符合纳入标准，然后使用数据提取表对文章进行评论，并生成和讨论了八个主题。在确定对实践的影响之前，本综述强调了衡量依从性的复杂性和困难，以及影响依从性的关键因素。参与 TYA 护理的所有各方（包括患者、专业人员、父母和同伴）之间的良好沟通和关系至关重要。根据系统评价的结果、与 TYA 依从性有关的其他文献以及作者的临床经验，对依从性模型进行了调整。个人因素和外部因素，以及治疗因素和与系统的相互作用，都会对患者的反应或依从能力产生影响。很明显，该领域需要更多高质量的定性和定量研究，重点是寻找直接提高该年龄组依从性的干预措施。根据系统评价的结果、与 TYA 依从性有关的其他文献以及作者的临床经验，对依从性模型进行了调整。个人因素和外部因素，以及治疗因素和与系统的相互作用，都会对患者的反应或依从能力产生影响。很明显，该领域需要更多高质量的定性和定量研究，重点是寻找直接提高该年龄组依从性的干预措施。根据系统评价的结果、与 TYA 依从性有关的其他文献以及作者的临床经验，对依从性模型进行了调整。个人因素和外部因素，以及治疗因素和与系统的相互作用，都会对患者的反应或依从能力产生影响。很明显，该领域需要更多高质量的定性和定量研究，重点是寻找直接提高该年龄组依从性的干预措施。s 反应或坚持的能力。很明显，该领域需要更多高质量的定性和定量研究，重点是寻找直接提高该年龄组依从性的干预措施。s 反应或坚持的能力。很明显，该领域需要更多高质量的定性和定量研究，重点是寻找直接提高该年龄组依从性的干预措施。