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The stressed orbitofrontal cortex.
Behavioral Neuroscience ( IF 1.9 ) Pub Date : 2021-03-25 , DOI: 10.1037/bne0000456
Michelle K Sequeira 1 , Shannon L Gourley 1
Affiliation  

Stressor exposure causes dendritic remodeling on excitatory neurons in multiple regions of the brain, including the orbitofrontal cortex (OFC). Additionally, stressor and exogenous stress hormone exposure impair cognitive functions that are dependent on the OFC. For this Special Issue on the OFC, we summarize current literature regarding how stress-prenatal, postnatal, and even inter-generational-affects OFC neuron structure in rodents. We discuss dendrite structure, dendritic spines, and gene expression. We aim to provide a focused resource for those interested in how stressors impact this heterogeneous brain region. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

中文翻译:

受压的眶额皮质。

应激源暴露会导致大脑多个区域的兴奋性神经元发生树突重塑,包括眶额皮质 (OFC)。此外,压力源和外源性压力激素暴露会损害依赖于 OFC 的认知功能。在本期关于 OFC 的特刊中,我们总结了当前有关压力-产前、产后甚至代际-如何影响啮齿动物的 OFC 神经元结构的文献。我们讨论树突结构、树突棘和基因表达。我们的目标是为那些对压力源如何影响这个异质大脑区域感兴趣的人提供集中资源。(PsycInfo 数据库记录 (c) 2021 APA,保留所有权利)。
更新日期:2021-03-29
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