In this study, the genotoxic effect of contaminants was assessed through detection of DNA damage using the micronucleus (MNs) test in erythrocytes from 149 flounder fish collected in two regions of the Gulf of Mexico (GoM). The frequency of microcytes (MCs) was also evaluated in the same group of fish collected from the Perdido Foldbelt (PF) and the Yucatan Platform (YP). The MCs frequency was different among locations of the YP (p = 0.011), while MNs frequency varied among locations of PF (p = 0.024). MCs and MNs values correlated with heavy metals from fish muscle, fish species and localities. Mean number, prevalence, and intensity of MCs and MNs correlated with Al, PAHs, depth, and locality. MNs frequency showed a species-specific association (p = 0.004). MNs and MCs were associated with heavy metals and PAHs from fish muscle and sediments, and the MNs frequency was species dependent.

在这项研究中，通过使用在墨西哥湾 (GoM) 两个地区采集的 149 条比目鱼的红细胞中的微核 (MNs) 测试检测 DNA 损伤来评估污染物的遗传毒性影响。还在从 Perdido Foldbelt (PF) 和 Yucatan Platform (YP) 收集的同一组鱼中评估了小细胞 (MCs) 的频率。YP 不同位置的 MCs 频率不同（p  = 0.011），而 PF 不同位置的 MNs 频率不同（p  = 0.024）。MCs 和 MNs 值与鱼肌肉、鱼类和产地的重金属相关。MCs 和 MNs 的平均数量、患病率和强度与 Al、PAHs、深度和位置相关。MNs 频率显示出物种特异性关联（p = 0.004)。MNs 和 MCs 与鱼类肌肉和沉积物中的重金属和 PAHs 相关，并且 MNs 频率取决于物种。