Introduction: Colorectal cancer (CRC) is the fourth leading cause of death with 1.4 million new cases occurring annually worldwide. High-quality clinical practice guidelines are needed to tailor high-quality individualized treatment. The aim of the present study was to evaluate the methodological quality of the current guidelines for the management of acute malignant left-sided colonic bowel obstruction. Methods: A systematic search of the literature was carried out using electronic databases. The Appraisal of Guidelines for Research and Evaluation (AGREE) II instrument was used to assess the quality of each guideline. Results: Search results returned a total of 14 guidelines appropriate for assessment. Both domain I (scope and purpose) and domain VI (editorial independence) were assessed with the same median score of 83%. The lowest scoring domain was domain V (applicability), scoring only 43%. The 2 guidelines that had the highest score were the National Institute for Health and Care Excellence (NICE) and Scottish Intercollegiate Guidelines Network (SIGN), each scoring 100%. However, there were significant variations in terms of quality. The NICE and New Zealand guidelines were voted unanimously for use unchanged, whilst 8 other guidelines were voted for use with modifications. Conclusion: Variation in guideline quality in CRC is a concern despite some clearly excellent published guidelines. All guidelines score poorly when it comes to describing how the guidelines could be applied. Lack of patient participation in guideline development is also a shortcoming that requires urgent redress.
Dig Surg

中文翻译：

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使用指南研究与评估 II 仪器的评估评估现行的恶性左侧结肠梗阻治疗指南

简介：结直肠癌 (CRC) 是第四大死亡原因，全球每年有 140 万新病例。需要高质量的临床实践指南来定制高质量的个体化治疗。本研究的目的是评估当前急性恶性左侧结肠肠梗阻治疗指南的方法学质量。方法：使用电子数据库对文献进行系统检索。研究和评估指南评估 (AGREE) II 工具用于评估每个指南的质量。结果：搜索结果总共返回了 14 条适合评估的指南。领域 I（范围和目的）和领域 VI（编辑独立性）的评估中位数得分相同，为 83%。得分最低的域是域 V（适用性），得分仅为 43%。得分最高的 2 个指南是国家健康与护理卓越研究所 (NICE) 和苏格兰校际指南网络 (SIGN)，每个指南的得分均为 100%。然而，在质量方面存在显着差异。NICE 和新西兰指南一致投票支持不变使用，而其他 8 项指南则被投票支持修改后使用。结论：尽管已经发布了一些非常出色的指南，但 CRC 中指南质量的差异仍然是一个问题。在描述如何应用指南时，所有指南得分都很低。缺乏患者参与指南制定也是一个需要紧急纠正的缺点。
挖掘外科