Abstract

A review of recent advances in the development of luminescent inorganic nanoparticles doped with rare earth ions, which can be used for biomedical applications, is presented. Luminescent nanomaterials doped with rare earth ions are characterized by physicochemical properties such as long luminescence time, large Stokes and/or anti-Stokes shifts, narrow luminescence bands, high photostability, and low toxicity. These materials can be considered to be a new generation of biosensors along with conventional molecular probes such as organic dyes, quantum dots, and lanthanide labels based on organic chelates.

中文翻译：

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掺杂稀土离子的发光纳米材料及其生物医学应用前景（综述）

摘要

本文介绍了可用于生物医学应用的掺有稀土离子的发光无机纳米粒子的最新研究进展。掺杂有稀土离子的发光纳米材料的特征在于其物理化学性质，例如发光时间长，斯托克斯和/或反斯托克斯位移大，发光谱带窄，光稳定性高，毒性低。这些材料与常规分子探针（例如有机染料，量子点和基于有机螯合物的镧系元素标记）一起被认为是新一代的生物传感器。