Abstract—

We report novel styrene derivatives of indole and pyranone. The possibility of their use as fluorogens for FAST protein were investigated. Derivatives of indole do not exhibit noticeable fluorogenic properties, while derivatives of pyranone exhibit superior fluorogenic potential; binding to a protein leads to an increase in fluorescence intensity and a emission red shift.

中文翻译：

---

吲哚和吡喃酮的苯乙烯衍生物作为FAST蛋白的荧光底物

摘要—

我们报道了吲哚和吡喃酮的新型苯乙烯衍生物。研究了将其用作FAST蛋白的荧光剂的可能性。吲哚的衍生物没有显着的发荧光特性，而吡喃酮的衍生物则具有更好的发荧光潜力。与蛋白质的结合导致荧光强度增加和发射红移。