Abstract—

6-O-Acetylated derivatives of D-hexopyranosides are valuable intermediates in synthetic carbohydrate chemistry. We have developed a new simple procedure for selective acetylation of the primary hydroxyl group in methyl D-hexopyranosides consisting in treatment with a mixture of acetic anhydride and acetic acid at 50°C. As a result, corresponding 6-acetates were formed in 40–50% yield.

中文翻译：

---

乙酸酐和乙酸的混合物在甲基D-六吡喃糖苷中伯羟基的选择性乙酰化

摘要—

D-己吡喃糖苷的6- O-乙酰化衍生物是合成碳水化合物化学中的有价值的中间体。我们开发了一种新的简单方法，用于选择性甲基化D-己基吡喃糖苷中伯羟基的乙酰化反应，包括在50°C下用乙酸酐和乙酸的混合物进行处理。结果，形成了相应的6-乙酸盐，产率为40-50％。