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Network functional connectivity underlying dissociable cognitive and affective components of empathy in adolescence
Neuropsychologia ( IF 2.0 ) Pub Date : 2021-03-19 , DOI: 10.1016/j.neuropsychologia.2021.107832
Drew E Winters 1 , Patrick J Pruitt 2 , Sadaaki Fukui 3 , Melissa A Cyders 4 , Barbara J Pierce 3 , Kathy Lay 3 , Jessica S Damoiseaux 5
Affiliation  

Empathy, the capacity to understand and share others' emotions, can occur through cognitive and affective components. These components are different conceptually, behaviorally, and in the brain. Neuroimaging task-based research in adolescents and adults document that cognitive empathy associates with the default mode and frontoparietal networks, whereas regions of the salience network underlie affective empathy. However, cognitive empathy is slower to mature than affective empathy and the extant literature reveals considerable developmental differences between adolescent and adult brains within and between these three networks. We extend previous work by examining empathy's association with functional connectivity within and between these networks in adolescents. Participants (n = 84, aged 13–17; 46.4% female) underwent resting state fMRI and completed self-report measures (Interpersonal Reactivity Index) for empathy as part of a larger Nathan-Kline Institute study. Regression analyses revealed adolescents reporting higher cognitive empathy had higher within DMN connectivity. Post hoc analysis revealed cognitive empathy's association within DMN connectivity is independent of affective empathy or empathy in general; and this association is driven by positive pairwise connections between the bilateral angular gyri and medial prefrontal cortex. These results suggest introspective cognitive processes related to the DMN are specifically important for cognitive empathy in adolescence.



中文翻译:

网络功能连接是青春期移情的可分离认知和情感成分的基础

同理心是理解和分享他人情绪的能力,可以通过认知和情感成分发生。这些成分在概念上、行​​为上和大脑中都是不同的。基于神经影像学任务的青少年和成人研究表明,认知移情与默认模式和额顶叶网络相关,而显着网络区域是情感移情的基础。然而,认知移情比情感移情成熟得更慢,现有的文献揭示了这三个网络内部和之间的青少年和成人大脑之间相当大的发育差异。我们通过检查移情与青少年这些网络内部和之间的功能连通性的关联来扩展以前的工作。参与者(n = 84,13-17 岁;46 岁。4% 的女性)接受了静息状态 fMRI 并完成了自我报告测量(人际反应指数)的同理心,这是 Nathan-Kline 研究所更大研究的一部分。回归分析显示,报告较高认知同理心的青少年在 DMN 连接中具有较高的水平。事后分析显示,认知移情在 DMN 连接中的关联通常独立于情感移情或移情;这种关联是由双边角回和内侧前额叶皮层之间的正成对连接驱动的。这些结果表明,与 DMN 相关的内省认知过程对于青春期的认知移情特别重要。回归分析显示,报告较高认知同理心的青少年在 DMN 连接中具有较高的水平。事后分析显示,认知移情在 DMN 连接中的关联通常独立于情感移情或移情;这种关联是由双边角回和内侧前额叶皮层之间的正成对连接驱动的。这些结果表明,与 DMN 相关的内省认知过程对于青春期的认知移情特别重要。回归分析显示,报告较高认知同理心的青少年在 DMN 连接中具有较高的水平。事后分析显示,认知移情在 DMN 连接中的关联通常独立于情感移情或移情;这种关联是由双边角回和内侧前额叶皮层之间的正成对连接驱动的。这些结果表明,与 DMN 相关的内省认知过程对于青春期的认知移情特别重要。这种关联是由双边角回和内侧前额叶皮层之间的正成对连接驱动的。这些结果表明,与 DMN 相关的内省认知过程对于青春期的认知移情特别重要。这种关联是由双边角回和内侧前额叶皮层之间的正成对连接驱动的。这些结果表明,与 DMN 相关的内省认知过程对于青春期的认知移情特别重要。

更新日期:2021-03-24
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