An 11-year-old domestic shorthair cat was referred for investigation of dry cough of 1-week duration and cardiomegaly. Echocardiography revealed pericardial effusion, and eosinophils were identified as the predominant cell type in fluid collected by pericardiocentesis. Thoracic computed tomography imaging and bronchoscopy were supportive of mild lower airway disease, while bronchoalveolar lavage confirmed eosinophilic inflammation and concurrent Mycoplasma felis infection. A few months after the initial presentation, there was clinical deterioration, and further investigation suggested intestinal lymphoma. It was hypothesized that pericardial effusion and lower airway inflammation were an early manifestation of hypereosinophilic syndrome, possibly as a paraneoplastic consequence of lymphoma.

一只 11 岁的家养短毛猫被转诊进行为期 1 周的干咳和心脏肥大的调查。超声心动图显示心包积液，在心包穿刺术收集的液体中，嗜酸性粒细胞被确定为主要细胞类型。胸部计算机断层扫描成像和支气管镜检查支持轻度下呼吸道疾病，而支气管肺泡灌洗证实嗜酸性炎症和并发猫支原体感染。初次就诊几个月后，临床恶化，进一步检查提示肠道淋巴瘤。据推测，心包积液和下呼吸道炎症是嗜酸性粒细胞增多综合征的早期表现，可能是淋巴瘤的副肿瘤后果。