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Changes of electrical impedance characteristics with the radiation induced damage on biological tissue constituents
Journal of X-Ray Science and Technology ( IF 1.7 ) Pub Date : 2021-03-13 , DOI: 10.3233/xst-210840
Sang Hyeong Kil 1 , Gyeong Rip Kim 2 , Moo Seok Lee 3 , Jong Hyeok Kwak 4 , Yeong Hyeon Lim 1 , Gun Do Kim 5 , Jong Kyu Lee 6
Affiliation  

This study analyzes the response of increasing radiation dose to the pork tenderloin tissue. Considering its significant cell structure, pork tenderloin tissue samples are selected for the experimental objects to measure their electrical impedance characteristics. This study proposes and investigates an effective approach to characterize the variation of the internal change of the components of pork tenderloin tissues caused by radiation. Changes in the pork tenderloin tissues are that the gap of the myotome is more far apart with increase of radiation dose because of the destroyed Myofibrils under the damage. With the increase of radiation dose, the impedance value of the pork tenderloin tissue decreases. Each of mean differences in the impedance values before and after irradiation dose under 1 Gy, 2 Gy and 4 Gy show 0.55±0.03, 1.09±0.14 and 1.97±0.14, respectively. However, the mean difference substantially increases to 13.08±0.16 at irradiation dose of 10 Gy. Thus, the cell membrane shows the most severe rupture at a radiation dose of 10 Gy. Changes in the microstructure of the irradiated pork tenderloin tissue samples are also checked and validated by a transmission electron microscope.

中文翻译:

生物组织成分辐射损伤后电阻抗特性的变化

本研究分析了增加辐射剂量对猪里脊肉组织的反应。考虑到其显着的细胞结构,选取猪里脊肉组织样本作为实验对象,以测量其电阻抗特性。本研究提出并研究了一种表征辐射引起的猪里脊肉组织成分内部变化的有效方法。猪里脊肉组织的变化是由于损伤下的肌原纤维被破坏,随着辐射剂量的增加,肌节的间隙越来越远。随着辐射剂量的增加,猪里脊肉组织的阻抗值降低。1 Gy、2 Gy和4 Gy照射剂量前后阻抗值的平均差异分别为0.55±0.03、1.09±0.14和1。分别为 97±0.14。然而,在 10 Gy 的辐照剂量下,平均差异显着增加到 13.08±0.16。因此,细胞膜在 10 Gy 的辐射剂量下表现出最严重的破裂。还通过透射电子显微镜检查和验证了辐照猪里脊肉组织样品的微观结构变化。
更新日期:2021-03-16
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