Loss of the metabolism and sleep regulating neuronal populations expressing orexin and oxytocin in the hypothalamus in amyotrophic lateral sclerosis,Neuropathology and Applied Neurobiology

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Loss of the metabolism and sleep regulating neuronal populations expressing orexin and oxytocin in the hypothalamus in amyotrophic lateral sclerosis
Neuropathology and Applied Neurobiology ( IF 4.0 ) Pub Date : 2021-03-23 , DOI: 10.1111/nan.12709
Sanaz Gabery ₁ , Rebekah M Ahmed _{2,

3} , Jashelle Caga ₃ , Matthew C Kiernan _{2,

3} , Glenda M Halliday ₄ , Åsa Petersén ₁

Affiliation

To determine the underlying cellular changes and clinical correlates associated with pathology of the hypothalamus in amyotrophic lateral sclerosis (ALS), as hypothalamic atrophy occurs in the preclinical phase of the disease.

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