The trials of finding non-conventional and alternative aquafeed ingredients are increasing. In this sense, this study evaluated the influence of coconut oil on the growth, feed utilization, immune, and antioxidative responses of Nile tilapia. Five test diets were formulated by mixing coconut oil with the other ingredients at 0, 1, 2, 3, and 4% of the total ration and presented for tilapia for 60 successive days. The final weight, SGR, weight gain (WG), and feed intake were superior in fish delivered 2% of coconut oil (P < 0.05). Concurrently, fish that received 2% coconut oil had lower FCR and higher PER than fish of the control and 4% groups (P < 0.05). Higher lipase activity was observed in fish of 2% and 3% levels than the remaining groups (P < 0.05). Besides, the amylase and protease activities of fish in 1%, 2%, and 3% groups were higher than the 0% level (P < 0.05). The total blood cholesterol, RBCs, and PCV showed higher values in Nile tilapia fed 2% and 3% coconut oil (P < 0.05). The lysozyme and phagocytic activities were higher in fish fed 2% and 3% levels than the control (P < 0.05), while the phagocytic index in 2% and 3% levels was higher than 0% and 4% levels. Furthermore, SOD and CAT were higher in fish fed 1%, 2%, and 3% than fish fed 0% and 4% levels while GSH was higher in fish of 1%, 2%, and 3% than fish fed 0% level (P < 0.05). However, the MDA level was markedly lower in fish fed 25, 3%, and 4% coconut oil than the 0% level (P < 0.05). The intestine’s histological structure in all groups appeared normal, forming of intestinal villi projecting from the intestinal wall. Also, the structure of the hepatopancreas had a normal architecture in all groups. To sum up, the inclusion of coconut oil at 2 to 3% is recommended as a replacer for fish oil in Nile tilapia diets.

寻找非常规和替代水产饲料成分的试验正在增加。从这个意义上说，本研究评估了椰子油对尼罗罗非鱼生长、饲料利用、免疫和抗氧化反应的影响。通过将椰子油与其他成分按总日粮的 0、1、2、3 和 4% 混合配制五种测试日粮，并连续 60 天提供罗非鱼。喂食 2% 椰子油的鱼的最终体重、SGR、增重 (WG) 和采食量均优于其他鱼类 ( P < 0.05)。同时，接受 2% 椰子油的鱼比对照组和 4% 组的鱼具有更低的 FCR 和更高的 PER（P < 0.05）。与其余组相比，在 2% 和 3% 水平的鱼中观察到更高的脂肪酶活性（P< 0.05)。此外，1%、2%、3%组鱼的淀粉酶和蛋白酶活性均高于0%水平（P < 0.05）。总血液胆固醇、红细胞和 PCV 在喂食 2% 和 3% 椰子油的尼罗罗非鱼中显示出更高的值 ( P < 0.05)。喂食2%和3%水平的鱼的溶菌酶和吞噬活性高于对照组（P < 0.05），而2%和3%水平的吞噬指数高于0%和4%水平。此外，饲喂 1%、2% 和 3% 的鱼的 SOD 和 CAT 高于饲喂 0% 和 4% 水平的鱼，而饲喂 1%、2% 和 3% 的鱼的 GSH 高于饲喂 0% 水平的鱼( P < 0.05)。然而，喂食 25%、3% 和 4% 椰子油的鱼的 MDA 水平明显低于喂食 0% 水平的鱼（P< 0.05)。各组肠道组织学结构均正常，形成肠壁突出的肠绒毛。此外，肝胰腺的结构在所有组中都具有正常的结构。总而言之，建议在尼罗罗非鱼饲料中加入 2% 至 3% 的椰子油作为鱼油的替代品。