The bioactive compounds, antioxidant activity, fatty acid composition, and antimicrobial activity of methanolic extracts of propolis collected from five locations in Turkey were examined. The total phenolics (TP) of propolis samples ranged from 79.17 to 174.51 mg GA/kg while the total flavonoids (TF) varied from 41.19 to 70.19 mg QE/kg; Muğla and Konya samples exhibited (p < 0.05) high TP and TF values, respectively. The antioxidant activity as DPPH varied between samples and was observed to be higher in the Muğla region than others, while as FRAP ranged from 1.17 to 3.74 µmol Fe (II)/g. HPLC analysis of phenolic compounds (PC) showed that pinocembrin was the major constituent, followed by pinobanksin. Analysis of fatty acids showed that eicosenoic acid was dominant in the Konia, Adana and Osmaniye samples, palmitic acid in the Erzurum sample, and cis-11, 14-eicosadienoic in the Muğla sample. All samples demonstrated varied inhibitory effects against gram-positive and gram-negative bacteria.

研究了从土耳其五个地点收集的蜂胶甲醇提取物的生物活性化合物、抗氧化活性、脂肪酸组成和抗菌活性。蜂胶样品的总酚（TP）范围为 79.17 至 174.51 mg GA/kg，而总黄酮（TF）范围为 41.19 至 70.19 mg QE/kg；Muğla 和 Konya 样品分别表现出 (p < 0.05) 高 TP 和 TF 值。DPPH 的抗氧化活性因样品而异，观察到 Muğla 地区的抗氧化活性高于其他地区，而 FRAP 的范围为 1.17 至 3.74 µmol Fe (II)/g。酚类化合物 (PC) 的 HPLC 分析表明松柏素是主要成分，其次是松柏素。脂肪酸分析表明，二十碳烯酸在 Konia、Adana 和 Osmaniye 样品中占优势，棕榈酸在 Erzurum 样品中占优势，Muğla 样品中的 cis-11, 14-eicosadienoic。所有样品对革兰氏阳性菌和革兰氏阴性菌均表现出不同的抑制作用。