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Biopolymers ( IF 3.2 ) Pub Date : 2021-03-24 , DOI: 10.1002/bip.23364


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Water plays an essential role in the structure and dynamics of DNA. Alcohol‐water solutions can be used as a medium to gauge the water‐DNA interactions because DNA immersed in these solutions is dehydrated relative to DNA immersed in pure water. The image illustrates an experiment probing the effects of ethanol concentration on the melting transition of DNA, in which the bonds between the two strands of double‐helix DNA break as the molecule is heated. In their paper, Andrew R. Wildes and team characterise the transition, reporting calorimetry and neutron scattering data analysed using a mesoscopic statistical mechanical theory. (DOI: 10.1002/bip.23422)


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水在DNA的结构和动力学中起着至关重要的作用。酒精水溶液可以用作衡量水与DNA相互作用的媒介,因为浸入这些溶液的DNA相对于浸入纯净水中的DNA脱水。该图像说明了探索乙醇浓度对DNA熔融转变的影响的实验,其中随着分子的加热,双螺旋DNA的两条链之间的键断裂。在他们的论文中,Andrew R. Wildes和团队描述了转变的特征,报告了使用介观统计力学理论分析的量热法和中子散射数据。(DOI:10.1002 / bip.23422)
更新日期:2021-03-24
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