Allium cepa extracts (AC) allow the fabrication of a biomaterial that, together with chitosan and PLGA, could be osteoconductive and promote a better and faster regeneration of bone tissue, with biocompatibility and biomineralization properties. In this work, scaffolds were developed by the thermally induced phase separation (TIPS) technique. An in vitro bioactivity analysis was performed using simulated body fluid (SBF). Scanning electron microscopy (SEM), energy dispersion spectroscopy, and infrared spectroscopy were used for the scaffolds characterization. The results showed a structure with a pore size distribution between 50 and 100 μm, which allowed the uniform formation of biological apatite crystals on the surface of the scaffolds. The chitosan/policaprolactone/Allium cepa scaffold (ChPAC) showed the most promising results with a ratio of P/Ca between 1.6 and 1.7, a value very close to that of hydroxyapatite.

洋葱提取物 (AC) 允许制造一种生物材料，该材料与壳聚糖和 PLGA 一起具有骨传导性，并促进骨组织更好更快的再生，具有生物相容性和生物矿化特性。在这项工作中，支架是通过热诱导相分离 (TIPS) 技术开发的。使用模拟体液 (SBF) 进行体外生物活性分析。使用扫描电子显微镜 (SEM)、能量色散光谱和红外光谱对支架进行表征。结果表明，孔径分布在 50 到 100 μm 之间的结构允许在支架表面均匀形成生物磷灰石晶体。壳聚糖/聚己内酯/洋葱 支架 (ChPAC) 显示出最有希望的结果，P/Ca 的比率在 1.6 和 1.7 之间，该值非常接近羟基磷灰石的值。