MicroRNA (miRNAs) are small non-coding RNA involved in gene expression regulation. Emerging evidences identify miRNAs as key regulators of beta cell physiology. Their role in fine-tuned gene expression regulation is crucial in the differentiation of insulin-producing cells and contributes to the acquisition and management of their unique phenotype. Dysregulation of miRNA expression causes beta cell dysfunction and promotes the development of different forms of diabetes mellitus.

中文翻译：

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microRNA在胰腺β细胞功能中的作用

MicroRNA (miRNA) 是参与基因表达调控的小型非编码 RNA。新出现的证据将 miRNA 确定为 β 细胞生理学的关键调节因子。它们在微调基因表达调控中的作用对于产生胰岛素的细胞的分化至关重要，并有助于获得和管理其独特的表型。miRNA表达失调导致β细胞功能障碍并促进不同形式糖尿病的发展。