When it comes to critical early post-acute TIA/stroke phase, there is a lack of a comprehensive multi-parametric telemonitoring system. The COVID-19 emergency, its related global mobility restrictions and fear of hospitalization further highlighted the need of a comprehensive solution. We aimed to design and test a pragmatic e-Health system based on multiparametric telemonitoring to support of TIA/stroke patients in sub-acute phase during the COVID-19 pandemic. We proposed a telemonitoring system and protocol for TIA/minor stroke patients during COVID-19 pandemic for patients at risk of stroke recurrence. This system involves the use of portable devices for BP/HR/SpO/temperature sensing, panic-button, gateway, and a dedicated ICT platform. The protocol is a 14-day multiparametric telemonitoring, therapy, and emergency intervention based on vital sign alteration notifications. We conducted a proof-of-concept validation test on 8 TIA/minor stroke patients in the early post-acute phase (< 14 days from ischemic event). The proposed solution allowed to promptly and remotely identify vital sign alterations at home during the early post-acute phase, allowing therapy and behavioral intervention adjustments. Also, we observed a significant improvement of quality of life, as well as a significant reduction of anxiety and depression status. TUQ showed ease of use, good interface quality and high user satisfaction of the proposed solution. The 3-month follow-up showed total adherence of prescribed therapy and no stroke/TIA recurrence or other emergency department admissions. The proposed e-Health solution and telemonitoring protocol may be highly useful for early post-acute remote patient management, thus supporting constant monitoring and patient adherence to the treatment pathway, especially during the COVID-19 emergency.

中文翻译：

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COVID-19 大流行期间急性 TIA/轻微中风早期后家庭患者远程监护的电子健康解决方案

当谈到关键的急性 TIA/中风后早期阶段时，缺乏全面的多参数远程监测系统。COVID-19 紧急情况、相关的全球流动限制以及对住院治疗的恐惧进一步凸显了全面解决方案的必要性。我们的目标是设计和测试基于多参数远程监测的实用电子健康系统，以在 COVID-19 大流行期间为亚急性阶段的 TIA/中风患者提供支持。我们为 COVID-19 大流行期间有中风复发风险的 TIA/轻微中风患者提出了远程监测系统和方案。该系统涉及使用用于 BP/HR/SpO/温度传感的便携式设备、紧急按钮、网关和专用 ICT 平台。该方案是基于生命体征变化通知的为期 14 天的多参数远程监测、治疗和紧急干预。我们对 8 名处于急性后早期阶段（缺血事件后 < 14 天）的 TIA/轻微中风患者进行了概念验证验证测试。所提出的解决方案允许在急性后早期阶段在家中快速远程识别生命体征变化，从而调整治疗和行为干预。此外，我们还观察到生活质量显着改善，焦虑和抑郁状态显着减少。TUQ 显示了所提出的解决方案的易用性、良好的界面质量和较高的用户满意度。3 个月的随访显示完全遵守规定的治疗，并且没有中风/TIA 复发或其他急诊入院。拟议的电子医疗解决方案和远程监测协议可能对于急性后远程患者管理非常有用，从而支持持续监测和患者遵守治疗途径，特别是在 COVID-19 紧急情况期间。