Excess salt intake is linked to cardiovascular disease as well as hypertension, but whether individual salt intake increases with age has not been studied. The present study was designed to test the hypothesis that individual salt intake increases with age in Japanese adults. In this retrospective observational follow-up study, men and women age ≥30 years who participated in a baseline health checkup (2008–2009) at our center and had a health checkup 10 years later (n = 2598) were enrolled and salt intake was estimated by spot urine analysis. Yearly changes in salt intake were also assessed in participants with complete annual data over the course of 10 years from baseline (n = 1543). The follow-up study demonstrated increased salt intake (8.8 ± 2.0 to 9.3 ± 2.1 g/d, P < .001) with increasing age (54.0 ± 9.7 to 64.0 ± 9.8 years). Salt intake increased year over year in participants who had a health checkup annually for the 10-year follow-up period (n = 1543; analysis of variance, P < .001). Cross-sectional analyses using propensity-matched model revealed similar regional levels of salt intake in the baseline period (8.9 ± 2.0 g/d, 55.8 ± 11.4 years, n = 5018) and at 10 years (8.8 ± 2.0 g/d, P = .21; 55.9 ± 13.0 years, P = .65, n = 5105). These results suggest that dietary salt intake increases with age in Japanese adults, which should be considered in devising population-based strategies to lower dietary salt intake.

过量的盐摄入与心血管疾病和高血压有关，但尚未研究个体盐摄入量是否随年龄增加。本研究旨在检验日本成年人个体盐摄入量随年龄增长而增加的假设。在这项回顾性观察性随访研究中，参加了我们中心基线健康检查（2008-2009）并在 10 年后进行健康检查的年龄≥30 岁的男性和女性（n = 2598）被纳入，盐摄入量为通过现场尿液分析估计。还评估了从基线开始 10 年期间具有完整年度数据的参与者（n = 1543）的盐摄入量的年度变化。后续研究表明盐摄入量增加（8.8 ± 2.0 至 9.3 ± 2.1 g/d，P< .001) 随着年龄的增长（54.0 ± 9.7 到 64.0 ± 9.8 岁）。在 10 年随访期间每年进行一次健康检查的参与者的盐摄入量逐年增加（n = 1543；方差分析，P < .001）。使用倾向匹配模型的横断面分析显示，基线期（8.9 ± 2.0 g/d，55.8 ± 11.4 年，n = 5018）和 10 年（8.8 ± 2.0 g/d，P  = .21；55.9 ± 13.0 年，P  = .65，n = 5105）。这些结果表明，日本成年人的膳食盐摄入量随着年龄的增长而增加，在制定基于人群的策略以降低膳食盐摄入量时应考虑这一点。