While Fusobacterium necrophorum historically has been considered normal tonsillar flora, recent studies from Europe and the US have suggested that carriage occur transiently in adolescence and young adulthood. However, no studies originating from Africa exist. In this cross-sectional study of tonsillar carriage of F. necrophorum, we aimed to investigate geographical differences in tonsillar carriage rates of F. necrophorum in healthy participants aged 15–25 years in Sweden and Zambia and further investigate the age distribution of tonsillar carriage in Zambia. Specimens were obtained by tonsillar swabs and analyzed with real-time PCR for F. necrophorum. In participants aged 15–25 years, tonsillar carriage was more common in Sweden 21/100 (21%) than in Zambia 6/192 (3%), p < 0.001. In Zambian participants aged above 25 years tonsillar carriage was rare 1/76 (1%). In conclusion, the high rate of tonsillar carriage in participants aged 15–25 years in Sweden has implications on the interpretation of tonsillar findings in patients with pharyngotonsillitis. Interestingly, a geographical difference was found with tonsillar carriage rarely identified in Zambia.

虽然历史上死尸梭杆菌被认为是正常的扁桃体菌群，但欧洲和美国最近的研究表明，携带发生在青春期和青年时期。但是，尚无源自非洲的研究。在这项关于F. necrophorum扁桃体携带的横断面研究中，我们旨在调查瑞典和赞比亚 15-25 岁健康参与者中F. necrophorum扁桃体携带率的地域差异，并进一步调查扁桃体携带率的年龄分布赞比亚。通过扁桃体拭子采集标本，并通过实时 PCR 分析F. necrophorum. 在 15-25 岁的参与者中，瑞典 21/100 (21%) 比赞比亚 6/192 (3%) 更常见扁桃体携带，p < 0.001。在赞比亚 25 岁以上的参与者中，扁桃体运输很少见 1/76 (1%)。总之，瑞典 15-25 岁参与者扁桃体的高携带率对咽扁桃体炎患者扁桃体检查结果的解释有影响。有趣的是，在赞比亚很少发现扁桃体携带有地理差异。