We explore how to configure an argon atmospheric-pressure plasma jet for enhancing its production of hydrogen peroxide (H₂O₂) in deionised water (DIW). The plasma jet consists of a quartz tube of 1.5mm inner diameter and 3mm outer diameter, with an upstream internal needle electrode (within the tube) and a downstream external cylindrical electrode (surrounding the tube). The plasma is operated by purging argon through the glass tube and applying a sinusoidal AC voltage to the internal needle electrode at 10 kV (peak–peak) with a frequency of 23.5 kHz. We study how the following operational parameters influence the production rate of H₂O₂ in water: tube length, inter-electrode separation distance, distance of the ground electrode from the tube orifice, distance between tube orifice and the DIW, argon flow rate and treatment time. By examining the electrical and optical properties of the plasma jet, we determine how the above operational parameters influence the major plasma processes that promote H₂O₂ generation through electron-induced dissociation reactions and UV photolysis within the plasma core and in the plasma afterglow; but with a caveat being that these processes are highly dependent on the water vapour content from the argon gas supply and ambient environment. We then demonstrate how the synergistic action between H₂O₂ and other plasma generated molecules at a plasma induced low pH in the DIW is highly effective at decontaminating common wound pathogens Gram-positive Staphylococus aureus and Gram-negative Pseudomonas aeruginosa. The information presented in this study is relevant in the design of medical plasma devices where production of plasma reactive species such as H₂O₂ at physiologically useful concentrations is needed to help realise the full clinical potential of the technology.

我们探索如何配置氩气常压等离子体射流，以提高其在去离子水 (DIW) 中的过氧化氢 (H ₂ O ₂ )产量。等离子射流由一个内径为 1.5mm 和外径为 3mm 的石英管、上游内部针电极（管内）和下游外部圆柱形电极（管周围）组成。等离子体是通过通过玻璃管吹扫氩气并以 23.5 kHz 的频率以 10 kV（峰-峰）向内部针电极施加正弦交流电压来操作的。我们研究以下操作参数如何影响 H ₂ O ₂的生产率在水中：管长、电极间间隔距离、接地电极与管口的距离、管口与 DIW 之间的距离、氩气流速和处理时间。通过检查等离子体射流的电学和光学特性，我们确定了上述操作参数如何影响主要的等离子体过程，这些过程通过等离子体核心内和等离子体余辉中的电子诱导解离反应和紫外线光解来促进 H ₂ O ₂生成；但需要注意的是，这些过程高度依赖于氩气供应和周围环境中的水蒸气含量。然后我们演示了 H ₂ O ₂之间的协同作用如何在 DIW 中由等离子体诱导的低 pH 值下的其他等离子体生成分子在净化常见伤口病原体革兰氏阳性金黄色葡萄球菌和革兰氏阴性铜绿假单胞菌方面非常有效。本研究中提供的信息与医疗等离子体设备的设计相关，在这些设备中，需要以生理学上有用的浓度生产诸如 H ₂ O _{2 之}类的等离子体活性物质，以帮助实现该技术的全部临床潜力。