Introduction: The Montreal Cognitive Assessment (MoCA) is a cognitive screening test widely used in clinical practice and suited for the detection of Mild Cognitive Impairment (MCI). The aims were to evaluate the psychometric properties of the Persian MoCA as a screening test for mild cognitive dysfunction in Iranian older adults and to assess its accuracy as a screening test for MCI and mild Alzheimer disease (AD). Method: One hundred twenty elderly with a mean age of 73.52 ± 7.46 years participated in this study. Twenty-one subjects had mild AD (MMSE score ≤21), 40 had MCI, and 59 were cognitively healthy controls. All the participants were administered the Mini-Mental State Examination (MMSE) to evaluate their general cognitive status. Also, a battery of comprehensive neuropsychological assessments was administered. Results: The mean score on the Persian version of the MoCA and the MMSE were 19.32 and 25.62 for MCI and 13.71 and 22.14 for AD patients, respectively. Using an optimal cutoff score of 22 the MoCA test detected 86% of MCI subjects, whereas the MMSE with a cutoff score of 26 detected 72% of MCI subjects. In AD patients with a cutoff score of 20, the MoCA had a sensitivity of 94% whereas the MMSE detected 61%. The specificity of the MoCA was 70% and 90% for MCI and AD, respectively. Discussion: The results of this study show that the Persian version of the MoCA is a reliable screening tool for detection of MCI and early stage AD. The MoCA is more sensitive than the MMSE in screening for cognitive impairment, proving it to be superior to MMSE in detecting MCI and mild AD.
Dement Geriatr Cogn Disord Extra 2021;11:51–57

中文翻译：

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波斯蒙特利尔认知评估在轻度认知障碍和阿尔茨海默病中的心理测量特性


简介：蒙特利尔认知评估（MoCA）是一种广泛应用于临床实践的认知筛查测试，适用于检测轻度认知障碍（MCI）。目的是评估波斯 MoCA 作为伊朗老年人轻度认知功能障碍筛查测试的心理测量特性，并评估其作为 MCI 和轻度阿尔茨海默病 (AD) 筛查测试的准确性。方法： 120名平均年龄为73.52±7.46岁的老年人参与了本研究。 21 名受试者患有轻度 AD（MMSE 评分≤21），40 名受试者患有 MCI，59 名受试者为认知健康对照。所有参与者都接受了简易精神状态检查（MMSE）以评估他们的一般认知状态。此外，还进行了一系列全面的神经心理学评估。结果：波斯语版 MoCA 和 MMSE 的 MCI 平均分分别为 19.32 分和 25.62 分，AD 患者的平均分分别为 13.71 分和 22.14 分。使用最佳截止分数 22，MoCA 测试检测到 86% 的 MCI 受试者，而截止分数为 26 的 MMSE 检测到 72% 的 MCI 受试者。在截止分数为 20 分的 AD 患者中，MoCA 的敏感度为 94%，而 MMSE 的敏感度为 61%。 MoCA 对 MCI 和 AD 的特异性分别为 70% 和 90%。讨论：本研究结果表明，波斯语版本的 MoCA 是检测 MCI 和早期 AD 的可靠筛查工具。 MoCA 在筛查认知障碍方面比 MMSE 更敏感，证明它在检测 MCI 和轻度 AD 方面优于 MMSE。

痴呆老年认知障碍额外 2021 年；11:51–57