Lack of knowledge around seroprevalence levels of COVID-19 in Poland was the reason for the implementation of a seroepidemiological study in the Katowice Region (2,100,000 inhabitants). In October–November 2020, a questionnaire examination and measurement of anti-SARS-CoV-2 IgG and IgM antibodies were performed in a random sample of the general population (n = 1167). The objectives of the study were to estimate the prevalence of IgG and IgM antibodies and to assess their host-related correlates. The prevalence of IgG seropositivity was 11.4% (95% CI: 9.5–13.2%) and IgM seropositivity was 4.6% (95% CI: 3.5–5.8%). Diagnosis of COVID-19 was found in 4.8% of subjects. A positive IgG test was statistically significantly associated with age (inverse relationship), a person’s contact with a COVID-19 patient, quarantine, and two symptoms in the past: fever and loss of smell/taste. Positive IgG tests were less prevalent in subjects who had diagnoses of arterial hypertension, diabetes, or rheumatologic disorders. IgM test positivity was associated with quarantine and loss of smell/taste only with no effect of chronic diseases found. In Poland, in the period October–November 2020, the prevalence of SARS-CoV-2 infection was larger than earlier estimates obtained in other European countries, probably reflecting the measurements obtained during the “second wave” of the epidemic.

中文翻译：

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波兰卡托维兹地区居民随机样本中抗 SARS-CoV-2 抗体的血清阳性率


由于缺乏对波兰 COVID-19 血清流行水平的了解，因此在卡托维兹地区（2,100,000 名居民）实施了血清流行病学研究。 2020年10月至11月，对一般人群（ n = 1167）进行了问卷调查和抗SARS-CoV-2 IgG和IgM抗体测定。该研究的目的是估计 IgG 和 IgM 抗体的流行率并评估其与宿主相关的相关性。 IgG 血清阳性率为 11.4%（95% CI：9.5-13.2%），IgM 血清阳性率为 4.6%（95% CI：3.5-5.8%）。 4.8% 的受试者被诊断出患有 COVID-19。 IgG 检测呈阳性与年龄（负相关）、与 COVID-19 患者的接触、隔离以及过去的两种症状（发烧和嗅觉/味觉丧失）在统计上显着相关。在诊断患有动脉高血压、糖尿病或风湿病的受试者中，IgG 检测呈阳性的情况较少见。 IgM 测试阳性仅与检疫和嗅觉/味觉丧失相关，未发现慢性疾病的影响。在波兰，2020 年 10 月至 11 月期间，SARS-CoV-2 感染流行率高于其他欧洲国家之前的估计值，这可能反映了疫情“第二波”期间获得的测量结果。