Introduction

This study was designed to understand the baseline salt intake of adult patients with hypertension in Shanxi Province, and to analyze the correlation between urinary sodium excretion and blood pressure.

Methods

From June 2018 to December 2019, 16 hospitals with regional representativeness and experimental conditions in Shanxi Province were selected, and 643 eligible adult inpatients with primary hypertension were enrolled from these hospitals. The ages of patients ranged from 18 to 80 years. A 24-h ambulatory blood pressure monitoring was performed, and morning urine sodium concentration and 24-h urine sodium excretion were measured. The correlation between urinary sodium excretion and blood pressure in adult patients with hypertension was analyzed.

Results

The baseline salt intake of the adult patient participants with hypertension in Shanxi Province was 11.51 g/day. The average 24-h urinary sodium excretion of all observed subjects was 191.90 ± 98.18 mmol. The 24-h urinary sodium excretion and morning urinary sodium concentration were significantly positively correlated with systolic and diastolic blood pressure following adjustment of confounding factors, including gender, age, body weight, and smoking.

Conclusion

The morning urine sodium concentration and 24-h urine sodium excretion were significantly positively correlated with blood pressure. High sodium excretion may be a risk factor for rhythm abnormalities in non-dipper pattern blood pressure. The control of urinary sodium concentration can thus be an important strategy for regulating abnormal blood pressure rhythm.

中文翻译：

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住院成人高血压患者尿钠排泄与血压的相关性

介绍

本研究旨在了解山西省成年高血压患者的基线盐摄入量，并分析尿钠排泄与血压之间的相关性。

方法

从2018年6月至2019年12月，选择了山西省16家具有区域代表性和实验条件的医院，并从这些医院招募了643名合格的原发性高血压成人住院患者。患者的年龄为18至80岁。进行24小时动态血压监测，并测量早晨尿钠浓度和24小时尿钠排泄。分析了成年高血压患者尿钠排泄与血压的相关性。

结果

山西省成年高血压患者的基线盐摄入量为11.51 g /天。所有观察对象的平均24小时尿钠排泄量为191.90±98.18 mmol。调整性别，年龄，体重和吸烟等混杂因素后，24小时尿钠排泄和早晨尿钠浓度与收缩压和舒张压显着正相关。

结论

早晨尿钠浓度和24小时尿钠排泄与血压呈显着正相关。高钠排泄可能是非北斗七星型血压节律异常的危险因素。因此，控制尿钠浓度可以成为调节异常血压​​节律的重要策略。