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Forgotten coindex of some non-toxic dendrimers structure used in targeted drug delivery
Main Group Metal Chemistry ( IF 1.8 ) Pub Date : 2020-01-01 , DOI: 10.1515/mgmc-2021-0004
Yasir Ali 1 , Zainab Bibi 2 , Quanita Kiran 3
Affiliation  

In recent past, porphyrin-based dendrimers have gained great attraction due to their usefulness in nano devices and photo-dynamic therapy. New technologies based upon nano-materials or dendrimers have potential to overcome the problems due to conventional drug delivery, like toxicity, poor solubility and poor release pattern of drugs. The chemical and physical properties of these highly branched nanometer sized dendrimers depend on their structure. In chemical network theory, various topological indices are used to predict chemical properties of molecules(dendrimers). Among many useful topological descriptors forgotten coindex is relatively less explored but is found very useful in material engineering, pharmaceutical and chemical industries. In this article, we consider some special dendrimers, like poly(propyl) ether imine, porphyrin, and zinc-porphyrin, and nanostars like D 1 [ k ] and D 2 [ k ] and compute forgotten coindex for these important structures.

中文翻译:

用于靶向药物递送的一些无毒树枝状大分子结构的被遗忘的共指数

近年来,基于卟啉的树枝状大分子由于其在纳米器件和光动力疗法中的有用性而获得了极大的吸引力。基于纳米材料或树状聚合物的新技术具有克服常规药物输送所带来的问题的潜力,例如毒性,不良的溶解性和不良的药物释放方式。这些高度支化的纳米级树枝状大分子的化学和物理性质取决于它们的结构。在化学网络理论中,各种拓扑指数用于预测分子(树枝状大分子)的化学性质。在许多有用的拓扑描述符中,相对较少地探索被遗忘的共指数,但发现它在材料工程,制药和化学工业中非常有用。在本文中,我们考虑一些特殊的树枝状聚合物,例如聚(丙基)醚亚胺,卟啉,
更新日期:2020-01-01
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