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Aiding diagnosis of childhood attention-deficit/hyperactivity disorder of the inattentive presentation: Discriminant function analysis of multi-domain measures including EEG
Biological Psychology ( IF 2.7 ) Pub Date : 2021-03-17 , DOI: 10.1016/j.biopsycho.2021.108080
Stuart J. Johnstone , Laura Parrish , Han Jiang , Da-Wei Zhang , Virginia Williams , Sun Li

Introduction

We developed a neurocognitive assessment tool (NCAT) in consultation with mental health professionals working with children with AD/HD as a diagnostic aid and screening tool. This study examines the predictive utility of NCAT in the classification of children with AD/HD Inattentive presentation.

Method

Fifty three children with AD/HD Inattentive presentation and 161 typically-developing children completed an NCAT assessment. Discriminant function analyses examined group membership prediction for separate components of NCAT and for the components combined.

Results

The combined model correctly classified 93.4 % of participants, with 91.4 % sensitivity and 93.9 % specificity. Contributions to classification were from SNAP-IV, psychological needs satisfaction, self-regulation, executive function performance, and EEG. The combined model resulted in a 9.3 % increase in specificity and 5.9 % increase in sensitivity compared to SNAP-IV alone.

Conclusions

NCAT provides good discrimination between children with and without AD/HD of the Inattentive presentation, and further investigation including other subtypes and comorbidities is warranted.



中文翻译:

协助诊断儿童注意力不集中/多动障碍:包括脑电图在内的多领域指标的判别功能分析

介绍

在与患有AD / HD患儿作为诊断辅助和筛查工具的精神卫生专业人员的协商下,我们开发了一种神经认知评估工具(NCAT)。这项研究检查了NCAT在AD / HD注意力不集中表现儿童分类中的预测效用。

方法

53名AD / HD注意力不集中的儿童和161名典型发育中的儿童完成了NCAT评估。判别函数分析检查了NCAT的单独组件和组合组件的组成员身份预测。

结果

组合模型正确分类了93.4%的参与者,敏感性为91.4%,特异性为93.9%。对分类的贡献来自SNAP-IV,心理需求满意度,自我调节,执行功能表现和脑电图。与单独的SNAP-IV相比,该组合模型的特异性提高了9.3%,敏感性提高了5.9%。

结论

NCAT可以对有无注意力不集中表现的AD / HD儿童和没有AD / HD的儿童做出良好的区分,因此有必要进行进一步的调查,包括其他亚型和合并症。

更新日期:2021-03-25
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